The main scientific interests of Dr. Bernardino’s research group are to identify and develop novel brain repair therapies for Parkinson’s disease (PD). Dr. Bernardino coordinated several projects aiming to investigate the role of several molecules (TNF-alpha, histamine, retinoic acid, microRNAs) in the context of PD. These studies focused in the ability of these molecules to induce neuroprotection while boost neurogenesis, neuronal maturation and function (Bernardino et al., 2012, Stem Cells; Ferreira et al., 2012, J Neuroinflammation; Rocha et al., 2016, Journal of Neuroinflammation; Saraiva et al., 2019, Scientific Reports). Dr. Bernardino’s team was also involved in the development and characterization of drug delivery systems for the controlled release of these molecules, aiming to boost their therapeutic effects (Santos et al., 2012, ACS Nano; Esteves et al, 2015, Frontiers in Aging Neuroscience; Ferreira et al., 2016, Nanoscale; Saraiva et al., 2016, J Control Rel). As a result of these research projects Dr. Bernardino was able to be the first and co-author of several publications in renowned journals from the field (e.g., Nature Communications, Stem Cells, Journal of Neuroscience, ACS Nano, PloS One, Journal of Controlled Release, Journal of Neuroinflammation, among others). Dr. Bernardino co-authored 53 peer review publications and 10 book chapters, and several communications presented in national and international meetings. For further information please visit the domain brainrepairgroup.wordpress.com.
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